The results document compelling brain processes in The Iceman and present intriguing possibilities for how his techniques might exert positive effects related to disorders of the immune system and even psychiatry. These investigations are part of the scientists' series of seminal studies launched in 2014 on how the human brain responds to thermoregulatory challenges. Their publication, "Brain Over Body: A study on the willful regulation of autonomic function during cold exposure," published in the journal NeuroImage, is the first to study how The Iceman's brain responds during experimentally controlled whole-body cold exposure. Wayne State University School of Medicine professors Otto Muzik, Ph.D., and Vaibhav Diwadkar, Ph.D., changed that.
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